{
  "size_class_table": {
    "small": {
      "weight_range": "≤20 lbs",
      "1": 15, "2": 24, "3": 28, "4": 32, "5": 36, "6": 40, "7": 44, "8": 48,
      "9": 52, "10": 56, "11": 60, "12": 64, "13": 68, "14": 72, "15": 76, "16": 80
    },
    "medium": {
      "weight_range": "21-50 lbs",
      "1": 15, "2": 24, "3": 28, "4": 33, "5": 37, "6": 42, "7": 47, "8": 51,
      "9": 56, "10": 60, "11": 65, "12": 69, "13": 74, "14": 78, "15": 83, "16": 87
    },
    "large": {
      "weight_range": "51-90 lbs",
      "1": 15, "2": 24, "3": 30, "4": 35, "5": 40, "6": 45, "7": 50, "8": 55,
      "9": 61, "10": 66, "11": 72, "12": 77, "13": 82, "14": 88, "15": 93, "16": 99
    },
    "giant": {
      "weight_range": ">90 lbs",
      "1": 15, "2": 24, "3": 32, "4": 37, "5": 42, "6": 49, "7": 56, "8": 64,
      "9": 71, "10": 78, "11": 86, "12": 93, "13": 101, "14": 108, "15": 115, "16": 123
    }
  },
  "size_class_table_source": {
    "chart_publisher": "American Animal Hospital Association (AAHA), 2019 AAHA Canine Life Stage Guidelines poster",
    "original_citation": "Dog Owner's Home Veterinary Handbook, Appendix B: Comparative Age of Dogs and Humans (Eldredge et al., 2007)",
    "url": "https://www.aaha.org/wp-content/uploads/globalassets/02-guidelines/canine-life-stage-2019/canine_and_feline_age_chart_poster.pdf"
  },
  "epigenetic_formula": {
    "formula": "human_age = 16 * ln(dog_age) + 31",
    "caveat": "Derived from DNA methylation data on 104 dogs, predominantly Labrador retrievers (ages 4 weeks to 16 years), compared against 320 humans (ages 1-103). The researchers stated the formula is largely based on Labrador retrievers alone and that future studies with other breeds are required to test its generalizability; results may differ significantly across breeds, especially small long-lived breeds versus larger short-lived ones. Do not present as breed- or size-general.",
    "source_url": "https://www.genome.gov/news/news-release/NHGRI-researchers-reframe-dog-to-human-aging-comparisons",
    "primary_paper": "Wang, Tan, Tian et al., 'Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome,' Cell Systems, 2020 (Ideker lab, UC San Diego)",
    "primary_paper_url": "https://www.cell.com/fulltext/S2405-4712(20)30203-9"
  },
  "seven_x_debunk_sources": [
    {
      "publisher": "American Veterinary Medical Association (AVMA)",
      "url": "https://www.avma.org/resources/pet-owners/petcare/senior-pet-care-faq",
      "quote": "Contrary to popular belief, dogs do not age at a rate of 7 human years per dog year."
    },
    {
      "publisher": "DogTime",
      "url": "https://dogtime.com/dog-health/general/20529-flaws-in-the-7-year-rule-how-accurate-are-dog-years",
      "quote": "Eight years in one breed is not equivalent to eight years in another. (David J. Waters, Purdue University Center on Aging); the 7-year rule likely originated as, in veterinarian William Fortney's words, 'a marketing ploy' to encourage annual vet visits."
    }
  ],
  "sources": [
    "https://www.aaha.org/wp-content/uploads/globalassets/02-guidelines/canine-life-stage-2019/canine_and_feline_age_chart_poster.pdf",
    "https://www.avma.org/resources/pet-owners/petcare/senior-pet-care-faq",
    "https://www.akc.org/expert-advice/health/how-to-calculate-dog-years-to-human-years/",
    "https://www.genome.gov/news/news-release/NHGRI-researchers-reframe-dog-to-human-aging-comparisons",
    "https://www.cell.com/fulltext/S2405-4712(20)30203-9",
    "https://dogtime.com/dog-health/general/20529-flaws-in-the-7-year-rule-how-accurate-are-dog-years"
  ]
}